Arizona MPJE (Pharmacy Jurisprudence) Practice Exam

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Which controlled substance schedule does Diphenoxylate belong to?

CI
CII
CIII
CIV

The correct answer is: CII

Diphenoxylate is classified as a Schedule II controlled substance. This classification is due to its potential for abuse and dependence, despite being used therapeutically in the treatment of diarrhea, often in combination with atropine to discourage misuse. The Schedule II designation reflects that this substance has a legitimate medical application but also significant risks associated with it, leading to stricter regulations regarding its prescription and dispensing. In contrast, other schedules such as III, IV, or I represent substances with lower potential for abuse or no accepted medical use, which is why Diphenoxylate's placement as a Schedule II substance is crucial in managing its use and preventing misuse.